Loss of glutamate transporter eaat2a leads to aberrant neuronal excitability, recurrent epileptic seizures, and basal hypoactivity

Astroglial excitatory amino acid transporter 2 (EAAT2, GLT‐1, and SLC1A2) regulates the duration and extent of neuronal excitation by removing glutamate from the synaptic cleft. Hence, an impairment in EAAT2 function could lead to an imbalanced brain network excitability. Here, we investigated the f...

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Detalles Bibliográficos
Autores principales: Hotz, Adriana L., Jamali, Ahmed, Rieser, Nicolas N., Niklaus, Stephanie, Aydin, Ecem, Myren‐Svelstad, Sverre, Lalla, Laetitia, Jurisch‐Yaksi, Nathalie, Yaksi, Emre, Neuhauss, Stephan C. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297858/
https://www.ncbi.nlm.nih.gov/pubmed/34716961
http://dx.doi.org/10.1002/glia.24106

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