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Chemical Modification of Phage‐Displayed Helix‐Loop‐Helix Peptides to Construct Kinase‐Focused Libraries

Conformationally constrained peptides hold promise as molecular tools in chemical biology and as a new modality in drug discovery. The construction and screening of a target‐focused library could be a promising approach for the generation of de novo ligands or inhibitors against target proteins. Her...

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Detalles Bibliográficos
Autores principales: Fujiwara, Daisuke, Mihara, Kousuke, Takayama, Ryo, Nakamura, Yusuke, Ueda, Mitsuhiro, Tsumuraya, Takeshi, Fujii, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297947/
https://www.ncbi.nlm.nih.gov/pubmed/34605137
http://dx.doi.org/10.1002/cbic.202100450