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Chemical Modification of Phage‐Displayed Helix‐Loop‐Helix Peptides to Construct Kinase‐Focused Libraries
Conformationally constrained peptides hold promise as molecular tools in chemical biology and as a new modality in drug discovery. The construction and screening of a target‐focused library could be a promising approach for the generation of de novo ligands or inhibitors against target proteins. Her...
Autores principales: | Fujiwara, Daisuke, Mihara, Kousuke, Takayama, Ryo, Nakamura, Yusuke, Ueda, Mitsuhiro, Tsumuraya, Takeshi, Fujii, Ikuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297947/ https://www.ncbi.nlm.nih.gov/pubmed/34605137 http://dx.doi.org/10.1002/cbic.202100450 |
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