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Development of an E. coli strain for cell‐free ADC manufacturing

Recent advances in cell‐free protein synthesis have enabled the folding and assembly of full‐length antibodies at high titers with extracts from prokaryotic cells. Coupled with the facile engineering of the Escherichia coli translation machinery, E. coli based in vitro protein synthesis reactions ha...

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Detalles Bibliográficos
Autores principales: Groff, Dan, Carlos, Nina A., Chen, Rishard, Hanson, Jeffrey A., Liang, Shengwen, Armstrong, Stephanie, Li, Xiaofan, Zhou, Sihong, Steiner, Alex, Hallam, Trevor J., Yin, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297987/
https://www.ncbi.nlm.nih.gov/pubmed/34655229
http://dx.doi.org/10.1002/bit.27961