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Protective effect of house screening against indoor Aedes aegypti in Mérida, Mexico: A cluster randomised controlled trial

OBJECTIVE: To evaluate the protective effect of house screening (HS) on indoor Aedes aegypti infestation, abundance and arboviral infection in Merida, Mexico. METHODS: In 2019, we performed a cluster randomised controlled trial (6 control and 6 intervention areas: 100 households/area). Intervention...

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Autores principales: Manrique‐Saide, Pablo, Herrera‐Bojórquez, Josué, Villegas‐Chim, Josué, Puerta‐Guardo, Henry, Ayora‐Talavera, Guadalupe, Parra‐Cardeña, Manuel, Medina‐Barreiro, Anuar, Ramírez‐Medina, Marypaz, Chi‐Ku, Aylin, Trujillo‐Peña, Emilio, Méndez‐Vales, Rosa E., Delfín‐González, Hugo, Toledo‐Romaní, María E., Bazzani, Roberto, Bolio‐Arceo, Edgardo, Gómez‐Dantés, Hector, Che‐Mendoza, Azael, Pavía‐Ruz, Norma, Kirstein, Oscar D., Vazquez‐Prokopec, Gonzalo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298035/
https://www.ncbi.nlm.nih.gov/pubmed/34587328
http://dx.doi.org/10.1111/tmi.13680
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author Manrique‐Saide, Pablo
Herrera‐Bojórquez, Josué
Villegas‐Chim, Josué
Puerta‐Guardo, Henry
Ayora‐Talavera, Guadalupe
Parra‐Cardeña, Manuel
Medina‐Barreiro, Anuar
Ramírez‐Medina, Marypaz
Chi‐Ku, Aylin
Trujillo‐Peña, Emilio
Méndez‐Vales, Rosa E.
Delfín‐González, Hugo
Toledo‐Romaní, María E.
Bazzani, Roberto
Bolio‐Arceo, Edgardo
Gómez‐Dantés, Hector
Che‐Mendoza, Azael
Pavía‐Ruz, Norma
Kirstein, Oscar D.
Vazquez‐Prokopec, Gonzalo M.
author_facet Manrique‐Saide, Pablo
Herrera‐Bojórquez, Josué
Villegas‐Chim, Josué
Puerta‐Guardo, Henry
Ayora‐Talavera, Guadalupe
Parra‐Cardeña, Manuel
Medina‐Barreiro, Anuar
Ramírez‐Medina, Marypaz
Chi‐Ku, Aylin
Trujillo‐Peña, Emilio
Méndez‐Vales, Rosa E.
Delfín‐González, Hugo
Toledo‐Romaní, María E.
Bazzani, Roberto
Bolio‐Arceo, Edgardo
Gómez‐Dantés, Hector
Che‐Mendoza, Azael
Pavía‐Ruz, Norma
Kirstein, Oscar D.
Vazquez‐Prokopec, Gonzalo M.
author_sort Manrique‐Saide, Pablo
collection PubMed
description OBJECTIVE: To evaluate the protective effect of house screening (HS) on indoor Aedes aegypti infestation, abundance and arboviral infection in Merida, Mexico. METHODS: In 2019, we performed a cluster randomised controlled trial (6 control and 6 intervention areas: 100 households/area). Intervention clusters received permanently fixed fiberglass HS on all windows and doors. The study included two cross‐sectional entomologic surveys, one baseline (dry season in May 2019) and one post‐intervention (PI, rainy season between September and October 2019). The presence and number of indoor Aedes females and blood‐fed females (indoor mosquito infestation) as well as arboviral infections with dengue (DENV) and Zika (ZIKV) viruses were evaluated in a subsample of 30 houses within each cluster. RESULTS: HS houses had significantly lower risk for having Aedes aegypti female mosquitoes (odds ratio [OR] = 0.56, 95% CI 0.33–0.97, p = 0.04) and blood‐fed females (OR = 0.53, 95% CI 0.28–0.97, p = 0.04) than unscreened households from the control arm. Compared to control houses, HS houses had significantly lower indoor Ae. aegypti abundance (rate ratio [RR] = 0.50, 95% CI 0.30–0.83, p = 0.01), blood‐fed Ae. aegypti females (RR = 0.48, 95% CI 0.27–0.85, p = 0.01) and female Ae. aegypti positive for arboviruses (OR = 0.29, 95% CI 0.10–0.86, p = 0.02). The estimated intervention efficacy in reducing Ae. aegypti arbovirus infection was 71%. CONCLUSIONS: These results provide evidence supporting the use of HS as an effective pesticide‐free method to control house infestations with Aedes aegypti and reduce the transmission of Aedes‐transmitted viruses such as DENV, chikungunya (CHIKV) and ZIKV.
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spelling pubmed-92980352022-07-21 Protective effect of house screening against indoor Aedes aegypti in Mérida, Mexico: A cluster randomised controlled trial Manrique‐Saide, Pablo Herrera‐Bojórquez, Josué Villegas‐Chim, Josué Puerta‐Guardo, Henry Ayora‐Talavera, Guadalupe Parra‐Cardeña, Manuel Medina‐Barreiro, Anuar Ramírez‐Medina, Marypaz Chi‐Ku, Aylin Trujillo‐Peña, Emilio Méndez‐Vales, Rosa E. Delfín‐González, Hugo Toledo‐Romaní, María E. Bazzani, Roberto Bolio‐Arceo, Edgardo Gómez‐Dantés, Hector Che‐Mendoza, Azael Pavía‐Ruz, Norma Kirstein, Oscar D. Vazquez‐Prokopec, Gonzalo M. Trop Med Int Health Research Articles OBJECTIVE: To evaluate the protective effect of house screening (HS) on indoor Aedes aegypti infestation, abundance and arboviral infection in Merida, Mexico. METHODS: In 2019, we performed a cluster randomised controlled trial (6 control and 6 intervention areas: 100 households/area). Intervention clusters received permanently fixed fiberglass HS on all windows and doors. The study included two cross‐sectional entomologic surveys, one baseline (dry season in May 2019) and one post‐intervention (PI, rainy season between September and October 2019). The presence and number of indoor Aedes females and blood‐fed females (indoor mosquito infestation) as well as arboviral infections with dengue (DENV) and Zika (ZIKV) viruses were evaluated in a subsample of 30 houses within each cluster. RESULTS: HS houses had significantly lower risk for having Aedes aegypti female mosquitoes (odds ratio [OR] = 0.56, 95% CI 0.33–0.97, p = 0.04) and blood‐fed females (OR = 0.53, 95% CI 0.28–0.97, p = 0.04) than unscreened households from the control arm. Compared to control houses, HS houses had significantly lower indoor Ae. aegypti abundance (rate ratio [RR] = 0.50, 95% CI 0.30–0.83, p = 0.01), blood‐fed Ae. aegypti females (RR = 0.48, 95% CI 0.27–0.85, p = 0.01) and female Ae. aegypti positive for arboviruses (OR = 0.29, 95% CI 0.10–0.86, p = 0.02). The estimated intervention efficacy in reducing Ae. aegypti arbovirus infection was 71%. CONCLUSIONS: These results provide evidence supporting the use of HS as an effective pesticide‐free method to control house infestations with Aedes aegypti and reduce the transmission of Aedes‐transmitted viruses such as DENV, chikungunya (CHIKV) and ZIKV. John Wiley and Sons Inc. 2021-10-21 2021-12 /pmc/articles/PMC9298035/ /pubmed/34587328 http://dx.doi.org/10.1111/tmi.13680 Text en © 2021 The Authors Tropical Medicine & International Health Published by John Wiley & Sons Ltd https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Manrique‐Saide, Pablo
Herrera‐Bojórquez, Josué
Villegas‐Chim, Josué
Puerta‐Guardo, Henry
Ayora‐Talavera, Guadalupe
Parra‐Cardeña, Manuel
Medina‐Barreiro, Anuar
Ramírez‐Medina, Marypaz
Chi‐Ku, Aylin
Trujillo‐Peña, Emilio
Méndez‐Vales, Rosa E.
Delfín‐González, Hugo
Toledo‐Romaní, María E.
Bazzani, Roberto
Bolio‐Arceo, Edgardo
Gómez‐Dantés, Hector
Che‐Mendoza, Azael
Pavía‐Ruz, Norma
Kirstein, Oscar D.
Vazquez‐Prokopec, Gonzalo M.
Protective effect of house screening against indoor Aedes aegypti in Mérida, Mexico: A cluster randomised controlled trial
title Protective effect of house screening against indoor Aedes aegypti in Mérida, Mexico: A cluster randomised controlled trial
title_full Protective effect of house screening against indoor Aedes aegypti in Mérida, Mexico: A cluster randomised controlled trial
title_fullStr Protective effect of house screening against indoor Aedes aegypti in Mérida, Mexico: A cluster randomised controlled trial
title_full_unstemmed Protective effect of house screening against indoor Aedes aegypti in Mérida, Mexico: A cluster randomised controlled trial
title_short Protective effect of house screening against indoor Aedes aegypti in Mérida, Mexico: A cluster randomised controlled trial
title_sort protective effect of house screening against indoor aedes aegypti in mérida, mexico: a cluster randomised controlled trial
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298035/
https://www.ncbi.nlm.nih.gov/pubmed/34587328
http://dx.doi.org/10.1111/tmi.13680
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