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Decoration of Squalenoyl‐Gemcitabine Nanoparticles with Squalenyl‐Hydroxybisphosphonate for the Treatment of Bone Tumors

Therapeutic perspectives of bone tumors such as osteosarcoma remain restricted due to the inefficacy of current treatments. We propose here the construction of a novel anticancer squalene‐based nanomedicine with bone affinity and retention capacity. A squalenyl‐hydroxybisphosphonate molecule was syn...

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Detalles Bibliográficos
Autores principales: Rodríguez‐Nogales, Carlos, Desmaële, Didier, Sebastián, Víctor, Couvreur, Patrick, Blanco‐Prieto, María J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298071/
https://www.ncbi.nlm.nih.gov/pubmed/34581019
http://dx.doi.org/10.1002/cmdc.202100464