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Decoration of Squalenoyl‐Gemcitabine Nanoparticles with Squalenyl‐Hydroxybisphosphonate for the Treatment of Bone Tumors
Therapeutic perspectives of bone tumors such as osteosarcoma remain restricted due to the inefficacy of current treatments. We propose here the construction of a novel anticancer squalene‐based nanomedicine with bone affinity and retention capacity. A squalenyl‐hydroxybisphosphonate molecule was syn...
Autores principales: | Rodríguez‐Nogales, Carlos, Desmaële, Didier, Sebastián, Víctor, Couvreur, Patrick, Blanco‐Prieto, María J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298071/ https://www.ncbi.nlm.nih.gov/pubmed/34581019 http://dx.doi.org/10.1002/cmdc.202100464 |
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