De novo design of type II topoisomerase inhibitors as potential antimicrobial agents targeting a novel binding region

By 2050, it is predicted that antimicrobial resistance will be responsible for 10 million global deaths annually, more deaths than cancer, costing the world economy $100 trillion. Clearly, strategies to address this problem are essential as bacterial evolution is rendering our current antibiotics in...

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Detalles Bibliográficos
Autores principales: Orritt, Kyle M., Feng, Lipeng, Newell, Juliette F., Sutton, Jack N., Grossman, Scott, Germe, Thomas, Abbott, Lauren R., Jackson, Holly L., Bury, Benjamin K. L., Maxwell, Anthony, McPhillie, Martin J., Fishwick, Colin W. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298182/
https://www.ncbi.nlm.nih.gov/pubmed/35919336
http://dx.doi.org/10.1039/d2md00049k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298182/
https://www.ncbi.nlm.nih.gov/pubmed/35919336
http://dx.doi.org/10.1039/d2md00049k

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