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A Bivalent Supramolecular GCP Ligand Enables Blocking of the Taspase1/Importin α Interaction
Taspase1 is a unique protease not only pivotal for embryonic development but also implicated in leukemia as well as solid tumors. As such, it is a promising target in cancer therapy, although only a limited number of Taspase1 inhibitors lacking general applicability are currently available. Here we...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298320/ https://www.ncbi.nlm.nih.gov/pubmed/34623765 http://dx.doi.org/10.1002/cmdc.202100640 |