A Distinct Macrophage Subset Mediating Tissue Destruction and Neovascularization in Giant Cell Arteritis: Implication of the YKL‐40/Interleukin‐13 Receptor α2 Axis

OBJECTIVE: Macrophages mediate inflammation, angiogenesis, and tissue destruction in giant cell arteritis (GCA). Serum levels of the macrophage‐associated protein YKL‐40 (chitinase 3–like protein 1), previously linked to angiogenesis and tissue remodeling, remain elevated in GCA despite glucocortico...

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Detalles Bibliográficos
Autores principales: van Sleen, Yannick, Jiemy, William F., Pringle, Sarah, van der Geest, Kornelis S. M., Abdulahad, Wayel H., Sandovici, Maria, Brouwer, Elisabeth, Heeringa, Peter, Boots, Annemieke M. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Vasculitis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298326/
https://www.ncbi.nlm.nih.gov/pubmed/34105308
http://dx.doi.org/10.1002/art.41887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298326/
https://www.ncbi.nlm.nih.gov/pubmed/34105308
http://dx.doi.org/10.1002/art.41887

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