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A Distinct Macrophage Subset Mediating Tissue Destruction and Neovascularization in Giant Cell Arteritis: Implication of the YKL‐40/Interleukin‐13 Receptor α2 Axis
OBJECTIVE: Macrophages mediate inflammation, angiogenesis, and tissue destruction in giant cell arteritis (GCA). Serum levels of the macrophage‐associated protein YKL‐40 (chitinase 3–like protein 1), previously linked to angiogenesis and tissue remodeling, remain elevated in GCA despite glucocortico...
Autores principales: | van Sleen, Yannick, Jiemy, William F., Pringle, Sarah, van der Geest, Kornelis S. M., Abdulahad, Wayel H., Sandovici, Maria, Brouwer, Elisabeth, Heeringa, Peter, Boots, Annemieke M. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298326/ https://www.ncbi.nlm.nih.gov/pubmed/34105308 http://dx.doi.org/10.1002/art.41887 |
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