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Vascularization of iNSC spheroid in a 3D spheroid‐on‐a‐chip platform enhances neural maturation

In vitro platforms for studying the human brain have been developed, and brain organoids derived from stem cells have been studied. However, current organoid models lack three‐dimensional (3D) vascular networks, limiting organoid proliferation, differentiation, and apoptosis. In this study, we creat...

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Detalles Bibliográficos
Autores principales: Shin, Nari, Kim, Youngtaek, Ko, Jihoon, Choi, Soon Won, Hyung, Sujin, Lee, Seung‐Eun, Park, Seunghyuk, Song, Jiyoung, Jeon, Noo Li, Kang, Kyung‐Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298365/
https://www.ncbi.nlm.nih.gov/pubmed/34716703
http://dx.doi.org/10.1002/bit.27978