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Population Pharmacokinetics and Initial Dosage Optimization of Tacrolimus in Pediatric Hematopoietic Stem Cell Transplant Patients

Background: There is a substantial lack of tacrolimus pharmacokinetic information in pediatric hematopoietic stem cell transplant (HSCT) patients. This study aimed to develop population pharmacokinetics (PopPK) of tacrolimus in pediatric HSCT patients and to devise model-guided dosage regimens. Meth...

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Detalles Bibliográficos
Autores principales:	Liu, Xiao-Lin, Guan, Yan-Ping, Wang, Ying, Huang, Ke, Jiang, Fu-Lin, Wang, Jian, Yu, Qi-Hong, Qiu, Kai-Feng, Huang, Min, Wu, Jun-Yan, Zhou, Dun-Hua, Zhong, Guo-Ping, Yu, Xiao-Xia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298550/ https://www.ncbi.nlm.nih.gov/pubmed/35873585 http://dx.doi.org/10.3389/fphar.2022.891648

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