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Hantzsch pre-column derivatization for simultaneous determination of alendronate sodium and its pharmacopoeial related impurity: Comparative study with synchronous fluorometry using fluorescamine

High performance liquid chromatographic (HPLC) method with a pre-column derivatization based on Hantzsch condensation reaction was applied for simultaneous determination of alendronate sodium (ALN) and its main related impurity, 4-Aminobutanoic acid (ABA) at its pharmacopeial limit. The separation o...

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Detalles Bibliográficos
Autores principales:	El-Yazbi, Amira F., El-Kimary, Eman I., Youssef, Rasha M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taiwan Food and Drug Administration 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298617/ https://www.ncbi.nlm.nih.gov/pubmed/30648573 http://dx.doi.org/10.1016/j.jfda.2018.05.009

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