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Development and validation of a new analytical HPLC method for simultaneous determination of the antidiabetic drugs, metformin and gliclazide

An efficient and simple HPLC method has been developed and validated for the simultaneous determination of gliclazide and metformin hydrochloride in bulk and was applied on marketed metformin and gliclazide products. The mobile phase used for the chromatographic runs consisted of 20 mM ammonium form...

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Detalles Bibliográficos
Autores principales: Gedawy, Ahmed, Al-Salami, Hani, Dass, Crispin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taiwan Food and Drug Administration 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298622/
https://www.ncbi.nlm.nih.gov/pubmed/30648585
http://dx.doi.org/10.1016/j.jfda.2018.06.007