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Human IPSC 3D brain model as a tool to study chemical-induced dopaminergic neuronal toxicity

Oxidative stress is caused by an imbalance between the generation and detoxification of reactive oxygen and nitrogen species (ROS/RNS). This imbalance plays an important role in brain aging and age-related neurodegenerative diseases. In the context of Parkinson’s disease (PD), the sensitivity of dop...

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Detalles Bibliográficos
Autores principales:	Pamies, David, Wiersma, Daphne, Katt, Moriah E., Zhao, Liang, Burtscher, Johannes, Harris, Georgina, Smirnova, Lena, Searson, Peter C., Hartung, Thomas, Hogberg, Helena T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298686/ https://www.ncbi.nlm.nih.gov/pubmed/35398340 http://dx.doi.org/10.1016/j.nbd.2022.105719

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