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Pharmacokinetics and pharmacodynamics of Abelacimab (MAA868), a novel dual inhibitor of Factor XI and Factor XIa

BACKGROUND: Factor XI (FXI) inhibition offers the promise of hemostasis‐sparing anticoagulation for the prevention and treatment of thromboembolic events. Abelacimab (MAA868) is a novel fully human monoclonal antibody that targets the catalytic domain and has dual activity against the inactive zymog...

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Detalles Bibliográficos
Autores principales:	Yi, B. Alexander, Freedholm, Debra, Widener, Nancy, Wang, Xiaohui, Simard, Emilie, Cullen, Constance, Al‐Saady, Naab M., Lepor, Norman E., Coulter, Sara, Lovern, Mark, Bloomfield, Dan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	HAEMOSTASIS
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298689/ https://www.ncbi.nlm.nih.gov/pubmed/34714969 http://dx.doi.org/10.1111/jth.15577

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