Strongly Truncated Dnaaf4 Plays a Conserved Role in Drosophila Ciliary Dynein Assembly as Part of an R2TP-Like Co-Chaperone Complex With Dnaaf6

Axonemal dynein motors are large multi-subunit complexes that drive ciliary movement. Cytoplasmic assembly of these motor complexes involves several co-chaperones, some of which are related to the R2TP co-chaperone complex. Mutations of these genes in humans cause the motile ciliopathy, Primary Cili...

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Detalles Bibliográficos
Autores principales: Lennon, Jennifer, zur Lage, Petra, von Kriegsheim, Alex, Jarman, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298768/
https://www.ncbi.nlm.nih.gov/pubmed/35873488
http://dx.doi.org/10.3389/fgene.2022.943197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298768/
https://www.ncbi.nlm.nih.gov/pubmed/35873488
http://dx.doi.org/10.3389/fgene.2022.943197

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