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A model‐based simulation of glycaemic control and body weight when switching from semaglutide to 3.0‐ and 4.5‐mg doses of once‐weekly dulaglutide

AIM: To evaluate HbA1c and body weight changes when semaglutide 0.5‐ or 1.0‐mg once‐weekly (QW) is switched to dulaglutide 3.0‐ or 4.5‐mg QW via exposure‐response modelling. METHODS: HbA1c and body weight time‐course models were developed and validated with data from the SUSTAIN 1 to 10 trials for s...

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Detalles Bibliográficos
Autores principales: Tham, Lai San, Pantalone, Kevin M., Dungan, Kathleen, Munir, Kashif, Tang, Cheng Cai, Konig, Manige, Kwan, Anita Y. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298861/
https://www.ncbi.nlm.nih.gov/pubmed/34697882
http://dx.doi.org/10.1111/dom.14582