The detection of germline and somatic BRCA1/2 genetic variants through parallel testing of patients with high‐grade serous ovarian cancer: a national retrospective audit

OBJECTIVE: To determine the frequency of germline and somatic pathogenic BRCA1 and BRCA2 variants in patients with high‐grade serous ovarian cancer tested by next‐generation sequencing (NGS), with the aim of defining the best strategy to be implemented in future routine testing. DESIGN: National ret...

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Detalles Bibliográficos
Autores principales: Frugtniet, B, Morgan, S, Murray, A, Palmer‐Smith, S, White, R, Jones, R, Hanna, L, Fuller, C, Hudson, E, Mullard, A, Quinton, AE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298909/
https://www.ncbi.nlm.nih.gov/pubmed/34657373
http://dx.doi.org/10.1111/1471-0528.16975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298909/
https://www.ncbi.nlm.nih.gov/pubmed/34657373
http://dx.doi.org/10.1111/1471-0528.16975

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