Cargando…

Interaction of Copper Trafficking Proteins with the Platinum Anticancer Drug Kiteplatin

The interaction of metallodrugs with proteins influences their mechanism of action and side effects. In the case of platinum drugs, copper transporters modulate sensitivity and resistance to these anticancer agents. To deepen the knowledge of the structural properties underlying the reactivity of pl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Barbanente, Alessandra, Galliani, Angela, Iacobazzi, Rosa Maria, Lasorsa, Alessia, Nardella, Maria Incoronata, Pennetta, Antonio, Margiotta, Nicola, Arnesano, Fabio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298912/ https://www.ncbi.nlm.nih.gov/pubmed/34727402 http://dx.doi.org/10.1002/cmdc.202100593

Ejemplares similares

Improvement of Kiteplatin Efficacy by a Benzoato Pt(IV) Prodrug Suitable for Oral Administration
por: Barbanente, Alessandra, et al.
Publicado: (2022)

Multinuclear Metal-Binding Ability of the N-Terminal Region of Human Copper Transporter Ctr1: Dependence Upon pH and Metal Oxidation State
por: Nardella, Maria Incoronata, et al.
Publicado: (2022)

Multi-Acting Mitochondria-Targeted Platinum(IV) Prodrugs of Kiteplatin with α-Lipoic Acid in the Axial Positions
por: Savino, Salvatore, et al.
Publicado: (2018)

Crystal Structure of the Human Copper Chaperone ATOX1 Bound to Zinc Ion
por: Mangini, Vincenzo, et al.
Publicado: (2022)

Cisplatin, Oxaliplatin, and Kiteplatin Subcellular Effects Compared in a Plant Model
por: Papadia, Paride, et al.
Publicado: (2017)

Cytotoxic pathways activated by multifunctional thiosemicarbazones targeting sigma-2 receptors in breast and lung carcinoma cells
por: Kopecka, Joanna, et al.
Publicado: (2023)

New Oxaliplatin-Pyrophosphato Analogs with Improved In Vitro Cytotoxicity
por: Barbanente, Alessandra, et al.
Publicado: (2021)

Oxidation of Human Copper Chaperone Atox1 and Disulfide Bond Cleavage by Cisplatin and Glutathione
por: Nardella, Maria I., et al.
Publicado: (2019)

Structural Elucidation of Cisplatin and Hydrated cis-Diammineplatinum(II) Complex Conjugated with Cyanocobalamin by Liquid Chromatography with Electrospray Ionization–Mass Spectrometry and Multistage Mass Spectrometry
por: Ventura, Giovanni, et al.
Publicado: (2018)

DNA‐Intercalative Platinum Anticancer Complexes Photoactivated by Visible Light
por: Shi, Huayun, et al.
Publicado: (2021)

Platinum(IV) Complexes of trans-1,2-diamino-4-cyclohexene: Prodrugs Affording an Oxaliplatin Analogue that Overcomes Cancer Resistance
por: Papadia, Paride, et al.
Publicado: (2020)

Activity and Trafficking of Copper-Transporting ATPases in Tumor Development and Defense against Platinum-Based Drugs
por: Petruzzelli, Raffaella, et al.
Publicado: (2019)

Diazido Mixed-Amine Platinum(IV) Anticancer Complexes Activatable by Visible-Light Form Novel DNA Adducts
por: Zhao, Yao, et al.
Publicado: (2013)

New Platinum(II) Complexes Affecting Different Biomolecular Targets in Resistant Ovarian Carcinoma Cells
por: Hyeraci, Mariafrancesca, et al.
Publicado: (2021)

Engineering Functions into Platinum and Platinum–Rhodium Nanoparticles in a One‐Step Microwave Irradiation Synthesis
por: Kalyva, Maria, et al.
Publicado: (2017)

In Vivo Anticancer Activity of a Nontoxic Inert Phenolato Titanium Complex: High Efficacy on Solid Tumors Alone and Combined with Platinum Drugs
por: Ganot, Nitzan, et al.
Publicado: (2018)

Targeting of radioactive platinum-bisphosphonate anticancer drugs to bone of high metabolic activity
por: Nadar, Robin A., et al.
Publicado: (2020)

Unravelling the anticancer potential of a square planar copper complex: toward non-platinum chemotherapy
por: Malik, Manzoor Ahmad, et al.
Publicado: (2021)

Anticancer Platinum Drugs Update
por: Ciarimboli, Giuliano
Publicado: (2021)

Chiral discrimination in platinum anticancer drugs.
por: Benedetti, Michele, et al.
Publicado: (2002)

Monofunctional Platinum(II) Anticancer Agents
por: Jin, Suxing, et al.
Publicado: (2021)

Single-Cell Chemistry of Photoactivatable Platinum Anticancer Complexes
por: Bolitho, Elizabeth M., et al.
Publicado: (2021)

Copper-Triggered Aggregation of Ubiquitin
por: Arnesano, Fabio, et al.
Publicado: (2009)

Structural Preferences in Phosphanylthiolato Platinum(II) Complexes
por: Duran, Josep, et al.
Publicado: (2015)

Synthesis, Characterization, and Cytotoxicity of the First Oxaliplatin Pt(IV) Derivative Having a TSPO Ligand in the Axial Position
por: Savino, Salvatore, et al.
Publicado: (2016)

Platinum Derivatives Effects on Anticancer Immune Response
por: Rébé, Cédric, et al.
Publicado: (2019)

Potential of Copper and Copper Compounds for Anticancer Applications
por: Ji, Peng, et al.
Publicado: (2023)

Fluorination Reactions at a Platinum Carbene Complex: Reaction Routes to SF(3), S(=O)F and Fluorido Complexes
por: Dirican, Dilcan, et al.
Publicado: (2021)

In Vitro Anticancer Properties of Copper Metallodendrimers
por: Hołota, Marcin, et al.
Publicado: (2019)

Copper trafficking in eukaryotic systems: current knowledge from experimental and computational efforts
por: Magistrato, Alessandra, et al.
Publicado: (2019)

Tryptophan regulates Drosophila zinc stores
por: Garay, Erika, et al.
Publicado: (2022)

Excessive copper impairs intrahepatocyte trafficking and secretion of selenoprotein P
por: Schwarz, Maria, et al.
Publicado: (2023)

A minimal structural variation can overcome tumour resistance of oxaliplatin: the case of 4,5-dehydrogenation of the cyclohexane ring
por: Papadia, Paride, et al.
Publicado: (2019)

Synthesis of a Novel Type of 2,3′‐BIMs via Platinum‐Catalysed Reaction of Indolylallenes with Indoles
por: Cooper, Lisa, et al.
Publicado: (2018)

In vitro cytotoxicity of combinations of dichloroacetate with anticancer platinum compounds
por: Olszewski, Ulrike, et al.
Publicado: (2010)

Novel Silver-Platinum Nanoparticles for Anticancer and Antimicrobial Applications
por: López Ruiz, Aida, et al.
Publicado: (2020)

Revisiting Platinum-Based Anticancer Drugs to Overcome Gliomas
por: Jeon, Jaewan, et al.
Publicado: (2021)

Ligand Evolution in the Photoactivatable Platinum(IV) Anticancer Prodrugs
por: Huang, Jingjing, et al.
Publicado: (2022)

Copy number footprints of platinum-based anticancer therapies
por: Gonzalez, Santiago, et al.
Publicado: (2023)

The Mechanisms of Current Platinum Anticancer Drug Resistance in the Glioma
por: Lu, Enzhou, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_51l45kmpj5v44cuecv7k9dv0vq