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The HDL mimetic CER‐001 remodels plasma lipoproteins and reduces kidney lipid deposits in inherited lecithin:cholesterol acyltransferase deficiency

BACKGROUND: Kidney failure is the major cause of morbidity and mortality in familial lecithin:cholesterol acyltransferase deficiency (FLD), a rare inherited lipid disorder with no cure. Lipoprotein X (LpX), an abnormal lipoprotein, is primarily accountable for nephrotoxicity. METHODS: CER‐001 was te...

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Detalles Bibliográficos
Autores principales:	Pavanello, Chiara, Turri, Marta, Strazzella, Arianna, Tulissi, Patrizia, Pizzolitto, Stefano, De Maglio, Giovanna, Nappi, Riccardo, Calabresi, Laura, Boscutti, Giuliano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299003/ https://www.ncbi.nlm.nih.gov/pubmed/34761839 http://dx.doi.org/10.1111/joim.13404

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