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Detection of antibodies against influenza D virus in swine veterinarians in Italy in 2004

Influenza D virus (IDV) was first isolated from a swine with respiratory disease symptoms in 2011 in the United States. Epidemiological and serological studies support the hypothesis that cattle represent the natural reservoir of IDV with periodical spillover events to other animal hosts. Little is...

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Autores principales: Trombetta, Claudia Maria, Montomoli, Emanuele, Di Bartolo, Ilaria, Ostanello, Fabio, Chiapponi, Chiara, Marchi, Serena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299042/
https://www.ncbi.nlm.nih.gov/pubmed/34811769
http://dx.doi.org/10.1002/jmv.27466
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author Trombetta, Claudia Maria
Montomoli, Emanuele
Di Bartolo, Ilaria
Ostanello, Fabio
Chiapponi, Chiara
Marchi, Serena
author_facet Trombetta, Claudia Maria
Montomoli, Emanuele
Di Bartolo, Ilaria
Ostanello, Fabio
Chiapponi, Chiara
Marchi, Serena
author_sort Trombetta, Claudia Maria
collection PubMed
description Influenza D virus (IDV) was first isolated from a swine with respiratory disease symptoms in 2011 in the United States. Epidemiological and serological studies support the hypothesis that cattle represent the natural reservoir of IDV with periodical spillover events to other animal hosts. Little is known about the seroprevalence in humans and in specific target groups such as veterinarians in Italy. This study was designed to assess the prevalence of antibodies against two influenza D lineages (D/660 and D/OK) in Italy in archived serum samples from veterinarians working with swine collected in 2004. Serum samples were tested by haemagglutination inhibition (HI) and virus neutralization (VN) assays. Results showed that 4.88% (4/82) of tested samples were positive for D/660 and 2.44% (2/82) for D/OK by HI assay. Three out of four samples showed positivity when tested by VN assay. Our data suggest undetected IDVs might have circulated and/or been introduced in Italy as early as 2004 at least in some animal species such as swine. In addition, it seems that the virus was circulating among veterinarians before the first isolation in 2011. This finding highlights the importance to continue monitoring the IDV spread in animals and humans for more detailed surveillance.
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spelling pubmed-92990422022-07-21 Detection of antibodies against influenza D virus in swine veterinarians in Italy in 2004 Trombetta, Claudia Maria Montomoli, Emanuele Di Bartolo, Ilaria Ostanello, Fabio Chiapponi, Chiara Marchi, Serena J Med Virol Short Communication Influenza D virus (IDV) was first isolated from a swine with respiratory disease symptoms in 2011 in the United States. Epidemiological and serological studies support the hypothesis that cattle represent the natural reservoir of IDV with periodical spillover events to other animal hosts. Little is known about the seroprevalence in humans and in specific target groups such as veterinarians in Italy. This study was designed to assess the prevalence of antibodies against two influenza D lineages (D/660 and D/OK) in Italy in archived serum samples from veterinarians working with swine collected in 2004. Serum samples were tested by haemagglutination inhibition (HI) and virus neutralization (VN) assays. Results showed that 4.88% (4/82) of tested samples were positive for D/660 and 2.44% (2/82) for D/OK by HI assay. Three out of four samples showed positivity when tested by VN assay. Our data suggest undetected IDVs might have circulated and/or been introduced in Italy as early as 2004 at least in some animal species such as swine. In addition, it seems that the virus was circulating among veterinarians before the first isolation in 2011. This finding highlights the importance to continue monitoring the IDV spread in animals and humans for more detailed surveillance. John Wiley and Sons Inc. 2021-11-27 2022-06 /pmc/articles/PMC9299042/ /pubmed/34811769 http://dx.doi.org/10.1002/jmv.27466 Text en © 2021 The Authors. Journal of Medical Virology published by Wiley Periodicals LLC https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Trombetta, Claudia Maria
Montomoli, Emanuele
Di Bartolo, Ilaria
Ostanello, Fabio
Chiapponi, Chiara
Marchi, Serena
Detection of antibodies against influenza D virus in swine veterinarians in Italy in 2004
title Detection of antibodies against influenza D virus in swine veterinarians in Italy in 2004
title_full Detection of antibodies against influenza D virus in swine veterinarians in Italy in 2004
title_fullStr Detection of antibodies against influenza D virus in swine veterinarians in Italy in 2004
title_full_unstemmed Detection of antibodies against influenza D virus in swine veterinarians in Italy in 2004
title_short Detection of antibodies against influenza D virus in swine veterinarians in Italy in 2004
title_sort detection of antibodies against influenza d virus in swine veterinarians in italy in 2004
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299042/
https://www.ncbi.nlm.nih.gov/pubmed/34811769
http://dx.doi.org/10.1002/jmv.27466
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