Cargando…
Detection of antibodies against influenza D virus in swine veterinarians in Italy in 2004
Influenza D virus (IDV) was first isolated from a swine with respiratory disease symptoms in 2011 in the United States. Epidemiological and serological studies support the hypothesis that cattle represent the natural reservoir of IDV with periodical spillover events to other animal hosts. Little is...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299042/ https://www.ncbi.nlm.nih.gov/pubmed/34811769 http://dx.doi.org/10.1002/jmv.27466 |
_version_ | 1784750854404833280 |
---|---|
author | Trombetta, Claudia Maria Montomoli, Emanuele Di Bartolo, Ilaria Ostanello, Fabio Chiapponi, Chiara Marchi, Serena |
author_facet | Trombetta, Claudia Maria Montomoli, Emanuele Di Bartolo, Ilaria Ostanello, Fabio Chiapponi, Chiara Marchi, Serena |
author_sort | Trombetta, Claudia Maria |
collection | PubMed |
description | Influenza D virus (IDV) was first isolated from a swine with respiratory disease symptoms in 2011 in the United States. Epidemiological and serological studies support the hypothesis that cattle represent the natural reservoir of IDV with periodical spillover events to other animal hosts. Little is known about the seroprevalence in humans and in specific target groups such as veterinarians in Italy. This study was designed to assess the prevalence of antibodies against two influenza D lineages (D/660 and D/OK) in Italy in archived serum samples from veterinarians working with swine collected in 2004. Serum samples were tested by haemagglutination inhibition (HI) and virus neutralization (VN) assays. Results showed that 4.88% (4/82) of tested samples were positive for D/660 and 2.44% (2/82) for D/OK by HI assay. Three out of four samples showed positivity when tested by VN assay. Our data suggest undetected IDVs might have circulated and/or been introduced in Italy as early as 2004 at least in some animal species such as swine. In addition, it seems that the virus was circulating among veterinarians before the first isolation in 2011. This finding highlights the importance to continue monitoring the IDV spread in animals and humans for more detailed surveillance. |
format | Online Article Text |
id | pubmed-9299042 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-92990422022-07-21 Detection of antibodies against influenza D virus in swine veterinarians in Italy in 2004 Trombetta, Claudia Maria Montomoli, Emanuele Di Bartolo, Ilaria Ostanello, Fabio Chiapponi, Chiara Marchi, Serena J Med Virol Short Communication Influenza D virus (IDV) was first isolated from a swine with respiratory disease symptoms in 2011 in the United States. Epidemiological and serological studies support the hypothesis that cattle represent the natural reservoir of IDV with periodical spillover events to other animal hosts. Little is known about the seroprevalence in humans and in specific target groups such as veterinarians in Italy. This study was designed to assess the prevalence of antibodies against two influenza D lineages (D/660 and D/OK) in Italy in archived serum samples from veterinarians working with swine collected in 2004. Serum samples were tested by haemagglutination inhibition (HI) and virus neutralization (VN) assays. Results showed that 4.88% (4/82) of tested samples were positive for D/660 and 2.44% (2/82) for D/OK by HI assay. Three out of four samples showed positivity when tested by VN assay. Our data suggest undetected IDVs might have circulated and/or been introduced in Italy as early as 2004 at least in some animal species such as swine. In addition, it seems that the virus was circulating among veterinarians before the first isolation in 2011. This finding highlights the importance to continue monitoring the IDV spread in animals and humans for more detailed surveillance. John Wiley and Sons Inc. 2021-11-27 2022-06 /pmc/articles/PMC9299042/ /pubmed/34811769 http://dx.doi.org/10.1002/jmv.27466 Text en © 2021 The Authors. Journal of Medical Virology published by Wiley Periodicals LLC https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Short Communication Trombetta, Claudia Maria Montomoli, Emanuele Di Bartolo, Ilaria Ostanello, Fabio Chiapponi, Chiara Marchi, Serena Detection of antibodies against influenza D virus in swine veterinarians in Italy in 2004 |
title | Detection of antibodies against influenza D virus in swine veterinarians in Italy in 2004 |
title_full | Detection of antibodies against influenza D virus in swine veterinarians in Italy in 2004 |
title_fullStr | Detection of antibodies against influenza D virus in swine veterinarians in Italy in 2004 |
title_full_unstemmed | Detection of antibodies against influenza D virus in swine veterinarians in Italy in 2004 |
title_short | Detection of antibodies against influenza D virus in swine veterinarians in Italy in 2004 |
title_sort | detection of antibodies against influenza d virus in swine veterinarians in italy in 2004 |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299042/ https://www.ncbi.nlm.nih.gov/pubmed/34811769 http://dx.doi.org/10.1002/jmv.27466 |
work_keys_str_mv | AT trombettaclaudiamaria detectionofantibodiesagainstinfluenzadvirusinswineveterinariansinitalyin2004 AT montomoliemanuele detectionofantibodiesagainstinfluenzadvirusinswineveterinariansinitalyin2004 AT dibartoloilaria detectionofantibodiesagainstinfluenzadvirusinswineveterinariansinitalyin2004 AT ostanellofabio detectionofantibodiesagainstinfluenzadvirusinswineveterinariansinitalyin2004 AT chiapponichiara detectionofantibodiesagainstinfluenzadvirusinswineveterinariansinitalyin2004 AT marchiserena detectionofantibodiesagainstinfluenzadvirusinswineveterinariansinitalyin2004 |