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Clinical Benefit of Niraparib to TKI/mTORi-Resistance Metastatic ccRCC With BAP1-Frame Shift Mutation: Case Report and Literature Review

Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cancer. The top four mutant genes affecting the occurrence and progression of ccRCC are VHL, PBRM1, BAP1, and SETD2, respectively. Tyrosine kinase/mammalian target of rapamycin inhibitors (TKI/mTORis) with or without immunot...

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Detalles Bibliográficos
Autores principales:	Lian, Bi-Jun, Zhang, Ke, Fang, Xu-Dong, Li, Feng, Dai, Zhao, Chen, Wei-Ying, Qi, Xiao-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299075/ https://www.ncbi.nlm.nih.gov/pubmed/35875073 http://dx.doi.org/10.3389/fonc.2022.927250

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