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Solid‐Phase‐Supported Chemoenzymatic Synthesis of a Light‐Activatable tRNA Derivative

Herein, we present a multi‐cycle chemoenzymatic synthesis of modified RNA with simplified solid‐phase handling to overcome size limitations of RNA synthesis. It combines the advantages of classical chemical solid‐phase synthesis and enzymatic synthesis using magnetic streptavidin beads and biotinyla...

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Detalles Bibliográficos
Autores principales:	Blümler, Anja, Schwalbe, Harald, Heckel, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299214/ https://www.ncbi.nlm.nih.gov/pubmed/34738704 http://dx.doi.org/10.1002/anie.202111613

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