Cellular Immune Dysfunction in Obstructive Sleep Apnea

Obstructive sleep apnea (OSA) is the most common sleep-related breathing disorder. Repetitive pauses in breathing during sleep cause a brief but recurrent decrease in oxygen saturation in organs and tissues (chronic intermittent tissue hypoxia). Many studies have proven a pro-inflammatory status in...

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Autores principales: Ludwig, Katharina, Huppertz, Tilman, Radsak, Markus, Gouveris, Haralampos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Surgery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299259/
https://www.ncbi.nlm.nih.gov/pubmed/35874140
http://dx.doi.org/10.3389/fsurg.2022.890377
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author Ludwig, Katharina
Huppertz, Tilman
Radsak, Markus
Gouveris, Haralampos
author_facet Ludwig, Katharina
Huppertz, Tilman
Radsak, Markus
Gouveris, Haralampos
author_sort Ludwig, Katharina
collection PubMed
description Obstructive sleep apnea (OSA) is the most common sleep-related breathing disorder. Repetitive pauses in breathing during sleep cause a brief but recurrent decrease in oxygen saturation in organs and tissues (chronic intermittent tissue hypoxia). Many studies have proven a pro-inflammatory status in OSA patients. However, few reports are available on the effects of OSA on the cellular immune system, mostly focusing on single immune cell types and their subtypes. The aim of this Mini-Review is to summarize these reports, as OSA is associated with a high prevalence and comorbidities such as atherosclerosis, which are known to involve the cellular immune system.
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spelling pubmed-92992592022-07-21 Cellular Immune Dysfunction in Obstructive Sleep Apnea Ludwig, Katharina Huppertz, Tilman Radsak, Markus Gouveris, Haralampos Front Surg Surgery Obstructive sleep apnea (OSA) is the most common sleep-related breathing disorder. Repetitive pauses in breathing during sleep cause a brief but recurrent decrease in oxygen saturation in organs and tissues (chronic intermittent tissue hypoxia). Many studies have proven a pro-inflammatory status in OSA patients. However, few reports are available on the effects of OSA on the cellular immune system, mostly focusing on single immune cell types and their subtypes. The aim of this Mini-Review is to summarize these reports, as OSA is associated with a high prevalence and comorbidities such as atherosclerosis, which are known to involve the cellular immune system. Frontiers Media S.A. 2022-07-06 /pmc/articles/PMC9299259/ /pubmed/35874140 http://dx.doi.org/10.3389/fsurg.2022.890377 Text en Copyright © 2022 Ludwig, Huppertz, Radsak and Gouveris. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Ludwig, Katharina
Huppertz, Tilman
Radsak, Markus
Gouveris, Haralampos
Cellular Immune Dysfunction in Obstructive Sleep Apnea
title Cellular Immune Dysfunction in Obstructive Sleep Apnea
title_full Cellular Immune Dysfunction in Obstructive Sleep Apnea
title_fullStr Cellular Immune Dysfunction in Obstructive Sleep Apnea
title_full_unstemmed Cellular Immune Dysfunction in Obstructive Sleep Apnea
title_short Cellular Immune Dysfunction in Obstructive Sleep Apnea
title_sort cellular immune dysfunction in obstructive sleep apnea
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299259/
https://www.ncbi.nlm.nih.gov/pubmed/35874140
http://dx.doi.org/10.3389/fsurg.2022.890377
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