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Bent pinkies: Quantifying fifth finger clinodactyly in a sample of U.S. adults
Mild curvature of the fifth finger (or clinodactyly) is a relatively common trait. While severe forms can cause functional impairment and are a feature of certain congenital syndromes, mild clinodactyly is considered a minor morphological variant. Despite exhibiting continuous variation, clinodactyl...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299322/ https://www.ncbi.nlm.nih.gov/pubmed/35857799 http://dx.doi.org/10.1371/journal.pone.0271734 |
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author | Lee, Myoung Keun Dahl, Zelda T. Anderton, Joel Maurer, Jennifer L. Marazita, Mary L. Shaffer, John R. Weinberg, Seth M. |
author_facet | Lee, Myoung Keun Dahl, Zelda T. Anderton, Joel Maurer, Jennifer L. Marazita, Mary L. Shaffer, John R. Weinberg, Seth M. |
author_sort | Lee, Myoung Keun |
collection | PubMed |
description | Mild curvature of the fifth finger (or clinodactyly) is a relatively common trait. While severe forms can cause functional impairment and are a feature of certain congenital syndromes, mild clinodactyly is considered a minor morphological variant. Despite exhibiting continuous variation, clinodactyly is rarely treated as a quantitative trait. Consequently, the degree of fifth finger curvature in the general population and the factors that impact this curvature are not well understood. In the present study, we measured fifth finger curvature in a sample of 1,295 U.S. adults and investigated the role of sex, age and body size. We found that clinodactyly exhibited a non-normal distribution. All participants displayed some degree of curvature, but it tended to be slight with an overall mean of 3.68 degrees (median: 3.58 degrees). In only 0.8% of cases did the curvature exceed the nominal 10-degree threshold for clinically meaningful clinodactyly. We did not find statically significant sex differences. Further, there was no meaningful relationship with height and only a weak positive relationship with age. We found that clinodactyly showed asymmetry; the curvature was greater on the left than on the right fifth finger (p < 2.2e(-16)), but this was not influenced by sex, age, or height. These results suggest the possibility that the kind of ubiquitous mild clinodactyly observed in the general population may be etiologically distinct from more rare and severe forms of the condition. |
format | Online Article Text |
id | pubmed-9299322 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-92993222022-07-21 Bent pinkies: Quantifying fifth finger clinodactyly in a sample of U.S. adults Lee, Myoung Keun Dahl, Zelda T. Anderton, Joel Maurer, Jennifer L. Marazita, Mary L. Shaffer, John R. Weinberg, Seth M. PLoS One Research Article Mild curvature of the fifth finger (or clinodactyly) is a relatively common trait. While severe forms can cause functional impairment and are a feature of certain congenital syndromes, mild clinodactyly is considered a minor morphological variant. Despite exhibiting continuous variation, clinodactyly is rarely treated as a quantitative trait. Consequently, the degree of fifth finger curvature in the general population and the factors that impact this curvature are not well understood. In the present study, we measured fifth finger curvature in a sample of 1,295 U.S. adults and investigated the role of sex, age and body size. We found that clinodactyly exhibited a non-normal distribution. All participants displayed some degree of curvature, but it tended to be slight with an overall mean of 3.68 degrees (median: 3.58 degrees). In only 0.8% of cases did the curvature exceed the nominal 10-degree threshold for clinically meaningful clinodactyly. We did not find statically significant sex differences. Further, there was no meaningful relationship with height and only a weak positive relationship with age. We found that clinodactyly showed asymmetry; the curvature was greater on the left than on the right fifth finger (p < 2.2e(-16)), but this was not influenced by sex, age, or height. These results suggest the possibility that the kind of ubiquitous mild clinodactyly observed in the general population may be etiologically distinct from more rare and severe forms of the condition. Public Library of Science 2022-07-20 /pmc/articles/PMC9299322/ /pubmed/35857799 http://dx.doi.org/10.1371/journal.pone.0271734 Text en © 2022 Lee et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Lee, Myoung Keun Dahl, Zelda T. Anderton, Joel Maurer, Jennifer L. Marazita, Mary L. Shaffer, John R. Weinberg, Seth M. Bent pinkies: Quantifying fifth finger clinodactyly in a sample of U.S. adults |
title | Bent pinkies: Quantifying fifth finger clinodactyly in a sample of U.S. adults |
title_full | Bent pinkies: Quantifying fifth finger clinodactyly in a sample of U.S. adults |
title_fullStr | Bent pinkies: Quantifying fifth finger clinodactyly in a sample of U.S. adults |
title_full_unstemmed | Bent pinkies: Quantifying fifth finger clinodactyly in a sample of U.S. adults |
title_short | Bent pinkies: Quantifying fifth finger clinodactyly in a sample of U.S. adults |
title_sort | bent pinkies: quantifying fifth finger clinodactyly in a sample of u.s. adults |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299322/ https://www.ncbi.nlm.nih.gov/pubmed/35857799 http://dx.doi.org/10.1371/journal.pone.0271734 |
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