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Bent pinkies: Quantifying fifth finger clinodactyly in a sample of U.S. adults

Mild curvature of the fifth finger (or clinodactyly) is a relatively common trait. While severe forms can cause functional impairment and are a feature of certain congenital syndromes, mild clinodactyly is considered a minor morphological variant. Despite exhibiting continuous variation, clinodactyl...

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Detalles Bibliográficos
Autores principales: Lee, Myoung Keun, Dahl, Zelda T., Anderton, Joel, Maurer, Jennifer L., Marazita, Mary L., Shaffer, John R., Weinberg, Seth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299322/
https://www.ncbi.nlm.nih.gov/pubmed/35857799
http://dx.doi.org/10.1371/journal.pone.0271734
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author Lee, Myoung Keun
Dahl, Zelda T.
Anderton, Joel
Maurer, Jennifer L.
Marazita, Mary L.
Shaffer, John R.
Weinberg, Seth M.
author_facet Lee, Myoung Keun
Dahl, Zelda T.
Anderton, Joel
Maurer, Jennifer L.
Marazita, Mary L.
Shaffer, John R.
Weinberg, Seth M.
author_sort Lee, Myoung Keun
collection PubMed
description Mild curvature of the fifth finger (or clinodactyly) is a relatively common trait. While severe forms can cause functional impairment and are a feature of certain congenital syndromes, mild clinodactyly is considered a minor morphological variant. Despite exhibiting continuous variation, clinodactyly is rarely treated as a quantitative trait. Consequently, the degree of fifth finger curvature in the general population and the factors that impact this curvature are not well understood. In the present study, we measured fifth finger curvature in a sample of 1,295 U.S. adults and investigated the role of sex, age and body size. We found that clinodactyly exhibited a non-normal distribution. All participants displayed some degree of curvature, but it tended to be slight with an overall mean of 3.68 degrees (median: 3.58 degrees). In only 0.8% of cases did the curvature exceed the nominal 10-degree threshold for clinically meaningful clinodactyly. We did not find statically significant sex differences. Further, there was no meaningful relationship with height and only a weak positive relationship with age. We found that clinodactyly showed asymmetry; the curvature was greater on the left than on the right fifth finger (p < 2.2e(-16)), but this was not influenced by sex, age, or height. These results suggest the possibility that the kind of ubiquitous mild clinodactyly observed in the general population may be etiologically distinct from more rare and severe forms of the condition.
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spelling pubmed-92993222022-07-21 Bent pinkies: Quantifying fifth finger clinodactyly in a sample of U.S. adults Lee, Myoung Keun Dahl, Zelda T. Anderton, Joel Maurer, Jennifer L. Marazita, Mary L. Shaffer, John R. Weinberg, Seth M. PLoS One Research Article Mild curvature of the fifth finger (or clinodactyly) is a relatively common trait. While severe forms can cause functional impairment and are a feature of certain congenital syndromes, mild clinodactyly is considered a minor morphological variant. Despite exhibiting continuous variation, clinodactyly is rarely treated as a quantitative trait. Consequently, the degree of fifth finger curvature in the general population and the factors that impact this curvature are not well understood. In the present study, we measured fifth finger curvature in a sample of 1,295 U.S. adults and investigated the role of sex, age and body size. We found that clinodactyly exhibited a non-normal distribution. All participants displayed some degree of curvature, but it tended to be slight with an overall mean of 3.68 degrees (median: 3.58 degrees). In only 0.8% of cases did the curvature exceed the nominal 10-degree threshold for clinically meaningful clinodactyly. We did not find statically significant sex differences. Further, there was no meaningful relationship with height and only a weak positive relationship with age. We found that clinodactyly showed asymmetry; the curvature was greater on the left than on the right fifth finger (p < 2.2e(-16)), but this was not influenced by sex, age, or height. These results suggest the possibility that the kind of ubiquitous mild clinodactyly observed in the general population may be etiologically distinct from more rare and severe forms of the condition. Public Library of Science 2022-07-20 /pmc/articles/PMC9299322/ /pubmed/35857799 http://dx.doi.org/10.1371/journal.pone.0271734 Text en © 2022 Lee et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Lee, Myoung Keun
Dahl, Zelda T.
Anderton, Joel
Maurer, Jennifer L.
Marazita, Mary L.
Shaffer, John R.
Weinberg, Seth M.
Bent pinkies: Quantifying fifth finger clinodactyly in a sample of U.S. adults
title Bent pinkies: Quantifying fifth finger clinodactyly in a sample of U.S. adults
title_full Bent pinkies: Quantifying fifth finger clinodactyly in a sample of U.S. adults
title_fullStr Bent pinkies: Quantifying fifth finger clinodactyly in a sample of U.S. adults
title_full_unstemmed Bent pinkies: Quantifying fifth finger clinodactyly in a sample of U.S. adults
title_short Bent pinkies: Quantifying fifth finger clinodactyly in a sample of U.S. adults
title_sort bent pinkies: quantifying fifth finger clinodactyly in a sample of u.s. adults
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299322/
https://www.ncbi.nlm.nih.gov/pubmed/35857799
http://dx.doi.org/10.1371/journal.pone.0271734
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