Expanding the epitranscriptome: Dihydrouridine in mRNA

Nucleotide modifications can markedly influence mRNA processing and metabolism. New studies, one in PLOS Biology, show that approximately 130 yeast mRNAs contain dihydrouridine, a derivative of uridine. Functional studies show that dihydrouridine, in some cases, can affect mRNA splicing.

Detalles Bibliográficos
Autores principales: Dixit, Sameer, Jaffrey, Samie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Primer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299342/
https://www.ncbi.nlm.nih.gov/pubmed/35857789
http://dx.doi.org/10.1371/journal.pbio.3001720
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author Dixit, Sameer
Jaffrey, Samie R.
author_facet Dixit, Sameer
Jaffrey, Samie R.
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description Nucleotide modifications can markedly influence mRNA processing and metabolism. New studies, one in PLOS Biology, show that approximately 130 yeast mRNAs contain dihydrouridine, a derivative of uridine. Functional studies show that dihydrouridine, in some cases, can affect mRNA splicing.
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spelling pubmed-92993422022-07-21 Expanding the epitranscriptome: Dihydrouridine in mRNA Dixit, Sameer Jaffrey, Samie R. PLoS Biol Primer Nucleotide modifications can markedly influence mRNA processing and metabolism. New studies, one in PLOS Biology, show that approximately 130 yeast mRNAs contain dihydrouridine, a derivative of uridine. Functional studies show that dihydrouridine, in some cases, can affect mRNA splicing. Public Library of Science 2022-07-20 /pmc/articles/PMC9299342/ /pubmed/35857789 http://dx.doi.org/10.1371/journal.pbio.3001720 Text en © 2022 Dixit, Jaffrey https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Primer
Dixit, Sameer
Jaffrey, Samie R.
Expanding the epitranscriptome: Dihydrouridine in mRNA
title Expanding the epitranscriptome: Dihydrouridine in mRNA
title_full Expanding the epitranscriptome: Dihydrouridine in mRNA
title_fullStr Expanding the epitranscriptome: Dihydrouridine in mRNA
title_full_unstemmed Expanding the epitranscriptome: Dihydrouridine in mRNA
title_short Expanding the epitranscriptome: Dihydrouridine in mRNA
title_sort expanding the epitranscriptome: dihydrouridine in mrna
topic Primer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299342/
https://www.ncbi.nlm.nih.gov/pubmed/35857789
http://dx.doi.org/10.1371/journal.pbio.3001720
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