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Single-Cell Transcriptomics of Immune Cells Reveal Diversity and Exhaustion Signatures in Non-Small-Cell Lung Cancer

Understanding immune cell phenotypes in the tumor microenvironment (TME) is essential for explaining and predicting progression of non-small cell lung cancer (NSCLC) and its response to immunotherapy. Here we describe the single-cell transcriptomics of CD45(+) immune cells from tumors, normal tissue...

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Detalles Bibliográficos
Autores principales: Zhao, Ying, Zhang, Qilin, Tu, Kailin, Chen, Yanmei, Peng, Yuxuan, Ni, Yinyun, Zhu, Guonian, Cheng, Cheng, Li, Yangqian, Xiao, Xue, Yu, Chunyan, Lu, Keying, Chen, Yaxin, Li, Chengpin, Tang, Jun, Wang, Gang, Luo, Wenxin, Zhang, Wengeng, Che, Guowei, Li, Weimin, Wang, Zhoufeng, Xie, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299430/
https://www.ncbi.nlm.nih.gov/pubmed/35874785
http://dx.doi.org/10.3389/fimmu.2022.854724