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Induction of Mucosal IgA–Mediated Protective Immunity Against Nontypeable Haemophilus influenzae Infection by a Cationic Nanogel–Based P6 Nasal Vaccine
Nontypeable Haemophilus influenzae (NTHi) strains form a major group of pathogenic bacteria that colonizes the nasopharynx and causes otitis media in young children. At present, there is no licensed vaccine for NTHi. Because NTHi colonizes the upper respiratory tract and forms biofilms that cause su...
Autores principales: | Nakahashi-Ouchida, Rika, Mori, Hiromi, Yuki, Yoshikazu, Umemoto, Shingo, Hirano, Takashi, Uchida, Yohei, Machita, Tomonori, Yamanoue, Tomoyuki, Sawada, Shin-ichi, Suzuki, Masashi, Fujihashi, Kohtaro, Akiyoshi, Kazunari, Kurono, Yuichi, Kiyono, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299436/ https://www.ncbi.nlm.nih.gov/pubmed/35874779 http://dx.doi.org/10.3389/fimmu.2022.819859 |
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