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Multivariate risk preferences in the quality‐adjusted life year model

The interest in multivariate and higher‐order risk preferences has increased. A growing body of literature has demonstrated the relevance and impact of these preferences, but for health the evidence is lacking. We measure multivariate and higher‐order risk preferences for quality of life (QoL) and l...

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Autores principales: Attema, Arthur E., Frasch, Jona J., L’Haridon, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299505/
https://www.ncbi.nlm.nih.gov/pubmed/34796588
http://dx.doi.org/10.1002/hec.4456
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author Attema, Arthur E.
Frasch, Jona J.
L’Haridon, Olivier
author_facet Attema, Arthur E.
Frasch, Jona J.
L’Haridon, Olivier
author_sort Attema, Arthur E.
collection PubMed
description The interest in multivariate and higher‐order risk preferences has increased. A growing body of literature has demonstrated the relevance and impact of these preferences, but for health the evidence is lacking. We measure multivariate and higher‐order risk preferences for quality of life (QoL) and longevity, the two attributes of the Quality‐Adjusted Life Year (QALY) model. We observe preferences for a positive correlation between these attributes and for pooling together a fixed loss in one of the attributes and a mean‐zero risk in the other, and for pooling together mean‐zero risks in QoL and longevity. The findings indicate that higher‐order risk preferences are stronger for health than for money. Furthermore, we test if preferences for a risky treatment for a disease affecting only QoL, depend on life expectancy. We find no such a relation, but there is a positive relation between riskiness of a comorbidity affecting life expectancy and risk aversion for a QoL treatment. We therefore observe no definitive deviation from the QALY model, although the model is more robust when expected longevity is high. Our findings suggest that the current practice of cost‐effectiveness analysis should be generalized to account for risk aversion in QoL and longevity, and higher‐order preferences.
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spelling pubmed-92995052022-07-21 Multivariate risk preferences in the quality‐adjusted life year model Attema, Arthur E. Frasch, Jona J. L’Haridon, Olivier Health Econ Research Articles The interest in multivariate and higher‐order risk preferences has increased. A growing body of literature has demonstrated the relevance and impact of these preferences, but for health the evidence is lacking. We measure multivariate and higher‐order risk preferences for quality of life (QoL) and longevity, the two attributes of the Quality‐Adjusted Life Year (QALY) model. We observe preferences for a positive correlation between these attributes and for pooling together a fixed loss in one of the attributes and a mean‐zero risk in the other, and for pooling together mean‐zero risks in QoL and longevity. The findings indicate that higher‐order risk preferences are stronger for health than for money. Furthermore, we test if preferences for a risky treatment for a disease affecting only QoL, depend on life expectancy. We find no such a relation, but there is a positive relation between riskiness of a comorbidity affecting life expectancy and risk aversion for a QoL treatment. We therefore observe no definitive deviation from the QALY model, although the model is more robust when expected longevity is high. Our findings suggest that the current practice of cost‐effectiveness analysis should be generalized to account for risk aversion in QoL and longevity, and higher‐order preferences. John Wiley and Sons Inc. 2021-11-18 2022-02 /pmc/articles/PMC9299505/ /pubmed/34796588 http://dx.doi.org/10.1002/hec.4456 Text en © 2021 The Authors. Health Economics published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Research Articles
Attema, Arthur E.
Frasch, Jona J.
L’Haridon, Olivier
Multivariate risk preferences in the quality‐adjusted life year model
title Multivariate risk preferences in the quality‐adjusted life year model
title_full Multivariate risk preferences in the quality‐adjusted life year model
title_fullStr Multivariate risk preferences in the quality‐adjusted life year model
title_full_unstemmed Multivariate risk preferences in the quality‐adjusted life year model
title_short Multivariate risk preferences in the quality‐adjusted life year model
title_sort multivariate risk preferences in the quality‐adjusted life year model
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299505/
https://www.ncbi.nlm.nih.gov/pubmed/34796588
http://dx.doi.org/10.1002/hec.4456
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