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Multivariate risk preferences in the quality‐adjusted life year model
The interest in multivariate and higher‐order risk preferences has increased. A growing body of literature has demonstrated the relevance and impact of these preferences, but for health the evidence is lacking. We measure multivariate and higher‐order risk preferences for quality of life (QoL) and l...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299505/ https://www.ncbi.nlm.nih.gov/pubmed/34796588 http://dx.doi.org/10.1002/hec.4456 |
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author | Attema, Arthur E. Frasch, Jona J. L’Haridon, Olivier |
author_facet | Attema, Arthur E. Frasch, Jona J. L’Haridon, Olivier |
author_sort | Attema, Arthur E. |
collection | PubMed |
description | The interest in multivariate and higher‐order risk preferences has increased. A growing body of literature has demonstrated the relevance and impact of these preferences, but for health the evidence is lacking. We measure multivariate and higher‐order risk preferences for quality of life (QoL) and longevity, the two attributes of the Quality‐Adjusted Life Year (QALY) model. We observe preferences for a positive correlation between these attributes and for pooling together a fixed loss in one of the attributes and a mean‐zero risk in the other, and for pooling together mean‐zero risks in QoL and longevity. The findings indicate that higher‐order risk preferences are stronger for health than for money. Furthermore, we test if preferences for a risky treatment for a disease affecting only QoL, depend on life expectancy. We find no such a relation, but there is a positive relation between riskiness of a comorbidity affecting life expectancy and risk aversion for a QoL treatment. We therefore observe no definitive deviation from the QALY model, although the model is more robust when expected longevity is high. Our findings suggest that the current practice of cost‐effectiveness analysis should be generalized to account for risk aversion in QoL and longevity, and higher‐order preferences. |
format | Online Article Text |
id | pubmed-9299505 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-92995052022-07-21 Multivariate risk preferences in the quality‐adjusted life year model Attema, Arthur E. Frasch, Jona J. L’Haridon, Olivier Health Econ Research Articles The interest in multivariate and higher‐order risk preferences has increased. A growing body of literature has demonstrated the relevance and impact of these preferences, but for health the evidence is lacking. We measure multivariate and higher‐order risk preferences for quality of life (QoL) and longevity, the two attributes of the Quality‐Adjusted Life Year (QALY) model. We observe preferences for a positive correlation between these attributes and for pooling together a fixed loss in one of the attributes and a mean‐zero risk in the other, and for pooling together mean‐zero risks in QoL and longevity. The findings indicate that higher‐order risk preferences are stronger for health than for money. Furthermore, we test if preferences for a risky treatment for a disease affecting only QoL, depend on life expectancy. We find no such a relation, but there is a positive relation between riskiness of a comorbidity affecting life expectancy and risk aversion for a QoL treatment. We therefore observe no definitive deviation from the QALY model, although the model is more robust when expected longevity is high. Our findings suggest that the current practice of cost‐effectiveness analysis should be generalized to account for risk aversion in QoL and longevity, and higher‐order preferences. John Wiley and Sons Inc. 2021-11-18 2022-02 /pmc/articles/PMC9299505/ /pubmed/34796588 http://dx.doi.org/10.1002/hec.4456 Text en © 2021 The Authors. Health Economics published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Research Articles Attema, Arthur E. Frasch, Jona J. L’Haridon, Olivier Multivariate risk preferences in the quality‐adjusted life year model |
title | Multivariate risk preferences in the quality‐adjusted life year model |
title_full | Multivariate risk preferences in the quality‐adjusted life year model |
title_fullStr | Multivariate risk preferences in the quality‐adjusted life year model |
title_full_unstemmed | Multivariate risk preferences in the quality‐adjusted life year model |
title_short | Multivariate risk preferences in the quality‐adjusted life year model |
title_sort | multivariate risk preferences in the quality‐adjusted life year model |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299505/ https://www.ncbi.nlm.nih.gov/pubmed/34796588 http://dx.doi.org/10.1002/hec.4456 |
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