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Pretreatment with Perlecan-Conjugated Laminin-E8 Fragment Enhances Maturation of Grafted Dopaminergic Progenitors in Parkinson’s Disease Model

The therapeutic effect of a cell replacement therapy for Parkinson’s disease (PD) depends on the proper maturation of grafted dopaminergic (DA) neurons and their functional innervation in the host brain. In the brain, laminin, an extracellular matrix protein, regulates signaling pathways for the sur...

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Detalles Bibliográficos
Autores principales:	Adachi, Hiromasa, Morizane, Asuka, Torikoshi, Sadaharu, Raudzus, Fabian, Taniguchi, Yukimasa, Miyamoto, Susumu, Sekiguchi, Kiyotoshi, Takahashi, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Tissue Engineering and Regenerative Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299512/ https://www.ncbi.nlm.nih.gov/pubmed/35605097 http://dx.doi.org/10.1093/stcltm/szac033

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