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Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia

The motor protein myosin-15 is necessary for the development and maintenance of mechanosensory stereocilia, and mutations in myosin-15 cause hereditary deafness. In addition to transporting actin regulatory machinery to stereocilia tips, myosin-15 directly nucleates actin filament (“F-actin”) assemb...

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Detalles Bibliográficos
Autores principales:	Gong, Rui, Jiang, Fangfang, Moreland, Zane G., Reynolds, Matthew J., de los Reyes, Santiago Espinosa, Gurel, Pinar, Shams, Arik, Heidings, James B., Bowl, Michael R., Bird, Jonathan E., Alushin, Gregory M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299544/ https://www.ncbi.nlm.nih.gov/pubmed/35857845 http://dx.doi.org/10.1126/sciadv.abl4733

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