Multiepitope supramolecular peptide nanofibers eliciting coordinated humoral and cellular antitumor immune responses

Subunit vaccines inducing antibodies against tumor-specific antigens have yet to be clinically successful. Here, we use a supramolecular α-helical peptide nanofiber approach to design epitope-specific vaccines raising simultaneous B cell, CD8(+) T cell, and CD4(+) T cell responses against combinatio...

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Detalles Bibliográficos
Autores principales: Wu, Yaoying, Wen, Hanning, Bernstein, Zachary J., Hainline, Kelly M., Blakney, Tykia S., Congdon, Kendra L., Snyder, David J., Sampson, John H., Sanchez-Perez, Luis, Collier, Joel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299545/
https://www.ncbi.nlm.nih.gov/pubmed/35857833
http://dx.doi.org/10.1126/sciadv.abm7833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299545/
https://www.ncbi.nlm.nih.gov/pubmed/35857833
http://dx.doi.org/10.1126/sciadv.abm7833

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