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Residual posttraumatic stress disorder symptoms after provision of brief behavioral intervention in low‐ and middle‐income countries: An individual‐patient data meta‐analysis

BACKGROUND: To address shortages of mental health specialists in low‐ and middle‐income countries, task‐shifting approaches have been employed to train nonspecialists to deliver evidence‐based scalable psychosocial interventions. Problem Management Plus (PM+) is a brief transdiagnostic nontrauma foc...

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Autores principales: Akhtar, Aemal, Koyiet, Phiona, Rahman, Atif, Schafer, Alison, Hamdani, Syed Usman, Cuijpers, Pim, Sijbrandij, Marit, Bryant, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299611/
https://www.ncbi.nlm.nih.gov/pubmed/34752690
http://dx.doi.org/10.1002/da.23221
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author Akhtar, Aemal
Koyiet, Phiona
Rahman, Atif
Schafer, Alison
Hamdani, Syed Usman
Cuijpers, Pim
Sijbrandij, Marit
Bryant, Richard A.
author_facet Akhtar, Aemal
Koyiet, Phiona
Rahman, Atif
Schafer, Alison
Hamdani, Syed Usman
Cuijpers, Pim
Sijbrandij, Marit
Bryant, Richard A.
author_sort Akhtar, Aemal
collection PubMed
description BACKGROUND: To address shortages of mental health specialists in low‐ and middle‐income countries, task‐shifting approaches have been employed to train nonspecialists to deliver evidence‐based scalable psychosocial interventions. Problem Management Plus (PM+) is a brief transdiagnostic nontrauma focused intervention for people affected by adversity. This study reports on the capacity of PM+ to address specific symptoms of posttraumatic stress disorder (PTSD). METHODS: Individual patient data from three randomised controlled trials were combined and analysed to observe the impacts of PM+ (n = 738) or enhanced treatment as usual (ETAU) (n = 742) interventions on specific PTSD symptoms at posttreatment and 3‐month follow‐up. The PTSD‐Checklist for DSM‐5 (PCL‐5) was used to index PTSD symptoms, and presence of each symptom was defined as moderate severity (score ≥ 2 on individual items). RESULTS: The average PCL‐5 score at baseline was 26.1 (SD: 16.8) with 463 (31.3%) scoring above 33, indicative of a diagnosis of PTSD. Following intervention, 12.5% and 5.8% of participants retained a score greater than 33 at postassessment and follow‐up, respectively. There was greater symptom reduction for PM+ than for ETAU for most symptoms. Hyperarousal symptoms were the most common residual symptoms after PM+, with more than 30% of participants reporting persistent sleep disturbance, concentration difficulties, and anger. CONCLUSION: PM+ led to greater reduction in symptoms relating to re‐experiencing and avoidance. The evidence indicates that strategies focusing on hyperarousal symptoms including sleep, concentration, and anger difficulties, could be strengthened in this brief intervention.
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spelling pubmed-92996112022-07-21 Residual posttraumatic stress disorder symptoms after provision of brief behavioral intervention in low‐ and middle‐income countries: An individual‐patient data meta‐analysis Akhtar, Aemal Koyiet, Phiona Rahman, Atif Schafer, Alison Hamdani, Syed Usman Cuijpers, Pim Sijbrandij, Marit Bryant, Richard A. Depress Anxiety Research Articles BACKGROUND: To address shortages of mental health specialists in low‐ and middle‐income countries, task‐shifting approaches have been employed to train nonspecialists to deliver evidence‐based scalable psychosocial interventions. Problem Management Plus (PM+) is a brief transdiagnostic nontrauma focused intervention for people affected by adversity. This study reports on the capacity of PM+ to address specific symptoms of posttraumatic stress disorder (PTSD). METHODS: Individual patient data from three randomised controlled trials were combined and analysed to observe the impacts of PM+ (n = 738) or enhanced treatment as usual (ETAU) (n = 742) interventions on specific PTSD symptoms at posttreatment and 3‐month follow‐up. The PTSD‐Checklist for DSM‐5 (PCL‐5) was used to index PTSD symptoms, and presence of each symptom was defined as moderate severity (score ≥ 2 on individual items). RESULTS: The average PCL‐5 score at baseline was 26.1 (SD: 16.8) with 463 (31.3%) scoring above 33, indicative of a diagnosis of PTSD. Following intervention, 12.5% and 5.8% of participants retained a score greater than 33 at postassessment and follow‐up, respectively. There was greater symptom reduction for PM+ than for ETAU for most symptoms. Hyperarousal symptoms were the most common residual symptoms after PM+, with more than 30% of participants reporting persistent sleep disturbance, concentration difficulties, and anger. CONCLUSION: PM+ led to greater reduction in symptoms relating to re‐experiencing and avoidance. The evidence indicates that strategies focusing on hyperarousal symptoms including sleep, concentration, and anger difficulties, could be strengthened in this brief intervention. John Wiley and Sons Inc. 2021-11-09 2022-01 /pmc/articles/PMC9299611/ /pubmed/34752690 http://dx.doi.org/10.1002/da.23221 Text en © 2021 The Authors. Depression and Anxiety published by Wiley Periodicals LLC https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Akhtar, Aemal
Koyiet, Phiona
Rahman, Atif
Schafer, Alison
Hamdani, Syed Usman
Cuijpers, Pim
Sijbrandij, Marit
Bryant, Richard A.
Residual posttraumatic stress disorder symptoms after provision of brief behavioral intervention in low‐ and middle‐income countries: An individual‐patient data meta‐analysis
title Residual posttraumatic stress disorder symptoms after provision of brief behavioral intervention in low‐ and middle‐income countries: An individual‐patient data meta‐analysis
title_full Residual posttraumatic stress disorder symptoms after provision of brief behavioral intervention in low‐ and middle‐income countries: An individual‐patient data meta‐analysis
title_fullStr Residual posttraumatic stress disorder symptoms after provision of brief behavioral intervention in low‐ and middle‐income countries: An individual‐patient data meta‐analysis
title_full_unstemmed Residual posttraumatic stress disorder symptoms after provision of brief behavioral intervention in low‐ and middle‐income countries: An individual‐patient data meta‐analysis
title_short Residual posttraumatic stress disorder symptoms after provision of brief behavioral intervention in low‐ and middle‐income countries: An individual‐patient data meta‐analysis
title_sort residual posttraumatic stress disorder symptoms after provision of brief behavioral intervention in low‐ and middle‐income countries: an individual‐patient data meta‐analysis
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299611/
https://www.ncbi.nlm.nih.gov/pubmed/34752690
http://dx.doi.org/10.1002/da.23221
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