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Slowing the loss of physical function in amyotrophic lateral sclerosis with edaravone: Post hoc analysis of ALSFRS‐R item scores in pivotal study MCI186‐19
INTRODUCTION: Phase 3 study MCI186‐19 demonstrated less loss of physical function with edaravone versus placebo, as measured by the revised Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS‐R) total score. A 1‐point drop in an individual ALSFRS‐R item may be clinically meaningful. We ass...
Autores principales: | Brooks, Benjamin Rix, Pioro, Erik P., Katz, Jonathan, Takahashi, Fumihiro, Takei, Koji, Zhang, Jeffrey, Apple, Stephen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299623/ https://www.ncbi.nlm.nih.gov/pubmed/34816454 http://dx.doi.org/10.1002/mus.27467 |
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