Cargando…

Incorporation of β‐Alanine in Cu(II) ATCUN Peptide Complexes Increases ROS Levels, DNA Cleavage and Antiproliferative Activity

Redox‐active Cu(II) complexes are able to form reactive oxygen species (ROS) in the presence of oxygen and reducing agents. Recently, Faller et al. reported that ROS generation by Cu(II) ATCUN complexes is not as high as assumed for decades. High complex stability results in silencing of the Cu(II)/...

Descripción completa

Detalles Bibliográficos
Autores principales: Heinrich, Julian, Bossak‐Ahmad, Karolina, Riisom, Mie, Haeri, Haleh H., Steel, Tasha R., Hergl, Vinja, Langhans, Alexander, Schattschneider, Corinna, Barrera, Jannis, Jamieson, Stephen M. F., Stein, Matthias, Hinderberger, Dariush, Hartinger, Christian G., Bal, Wojciech, Kulak, Nora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299640/
https://www.ncbi.nlm.nih.gov/pubmed/34658072
http://dx.doi.org/10.1002/chem.202102601