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Incorporation of β‐Alanine in Cu(II) ATCUN Peptide Complexes Increases ROS Levels, DNA Cleavage and Antiproliferative Activity
Redox‐active Cu(II) complexes are able to form reactive oxygen species (ROS) in the presence of oxygen and reducing agents. Recently, Faller et al. reported that ROS generation by Cu(II) ATCUN complexes is not as high as assumed for decades. High complex stability results in silencing of the Cu(II)/...
Autores principales: | Heinrich, Julian, Bossak‐Ahmad, Karolina, Riisom, Mie, Haeri, Haleh H., Steel, Tasha R., Hergl, Vinja, Langhans, Alexander, Schattschneider, Corinna, Barrera, Jannis, Jamieson, Stephen M. F., Stein, Matthias, Hinderberger, Dariush, Hartinger, Christian G., Bal, Wojciech, Kulak, Nora |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299640/ https://www.ncbi.nlm.nih.gov/pubmed/34658072 http://dx.doi.org/10.1002/chem.202102601 |
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