NKG2A is a late immune checkpoint on CD8 T cells and marks repeated stimulation and cell division

The surface inhibitory receptor NKG2A forms heterodimers with the invariant CD94 chain and is expressed on a subset of activated CD8 T cells. As antibodies to block NKG2A are currently tested in several efficacy trials for different tumor indications, it is important to characterize the NKG2A(+) CD8...

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Detalles Bibliográficos
Autores principales: Borst, Linda, Sluijter, Marjolein, Sturm, Gregor, Charoentong, Pornpimol, Santegoets, Saskia J., van Gulijk, Mandy, van Elsas, Marit J., Groeneveldt, Christianne, van Montfoort, Nadine, Finotello, Francesca, Trajanoski, Zlatko, Kiełbasa, Szymon M., van der Burg, Sjoerd H., van Hall, Thorbald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Tumor Immunology and Microenvironment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299709/
https://www.ncbi.nlm.nih.gov/pubmed/34716584
http://dx.doi.org/10.1002/ijc.33859

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