An integrative genomics approach identifies KDM4 as a modulator of trained immunity

Innate immune cells are able to build memory characteristics via a process termed “trained immunity.” Host factors that influence the magnitude of the individual trained immunity response remain largely unknown. Using an integrative genomics approach, our study aimed to prioritize and understand the...

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Detalles Bibliográficos
Autores principales: Moorlag, Simone J.C.F.M., Matzaraki, Vasiliki, van Puffelen, Jelmer H., van der Heijden, Charlotte, Keating, Sam, Groh, Laszlo, Röring, Rutger Jan, Bakker, Olivier B., Mourits, Vera P., Koeken, Valerie A.C.M., de Bree, L. Charlotte J., Smeekens, Sanne P., Oosting, Marije, Gamboa, Raúl Aguirre, Riksen, Niels P., Xavier, Ramnik J., Wijmenga, Cisca, Kumar, Vinod, van Crevel, Reinout, Novakovic, Boris, Joosten, Leo A.B., Li, Yang, Netea, Mihai G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Systems immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299854/
https://www.ncbi.nlm.nih.gov/pubmed/34821391
http://dx.doi.org/10.1002/eji.202149577

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