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Hepatitis E virus RNA‐dependent RNA polymerase is involved in RNA replication and infectious particle production

BACKGROUND AND AIMS: Hepatitis E virus (HEV) is one of the most common causes of acute hepatitis worldwide. Its positive‐strand RNA genome encodes three open reading frames (ORF). ORF1 is translated into a large protein composed of multiple domains and is known as the viral replicase. The RNA‐depend...

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Detalles Bibliográficos
Autores principales: Oechslin, Noémie, Da Silva, Nathalie, Szkolnicka, Dagmara, Cantrelle, François‐Xavier, Hanoulle, Xavier, Moradpour, Darius, Gouttenoire, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300124/
https://www.ncbi.nlm.nih.gov/pubmed/34387882
http://dx.doi.org/10.1002/hep.32100