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A Novel Inhibitor INF 39 Promotes Osteogenesis via Blocking the NLRP3/IL-1β Axis

PURPOSE: A balance between osteoblasts and osteoclasts is essential to maintain skeletal integrity, regulating bone metabolism and bone remodeling. The nucleotide binding oligomerization domain, leucine-rich repeat and pyrin domain containing protein 3 (NLRP3) inflammasome is known as a cytosolic co...

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Detalles Bibliográficos
Autores principales:	Chen, Wenxiang, Tang, Pan, Fan, Shunwu, Jiang, Xuesheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300331/ https://www.ncbi.nlm.nih.gov/pubmed/35872849 http://dx.doi.org/10.1155/2022/7250578

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