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LY450139 Inhibited Ti-Particle-Induced Bone Dissolution via Suppressing Notch and NF-κB Signaling Pathways

Aseptic loosening of the prosthesis caused by wear-particle-induced osteolysis is a long-term complication and one of the most common reasons for the failure of joint implants. The primary cause of aseptic loosening of the prosthesis is overactive bone resorption caused by wear-particle-activated os...

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Detalles Bibliográficos
Autores principales:	Gao, Jijian, Wu, Peng, Chi, Yingjun, Xu, Hongyu, Zhao, Yong, Song, Nanyan, Mao, Yuanqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300553/ https://www.ncbi.nlm.nih.gov/pubmed/35588014 http://dx.doi.org/10.1007/s00223-022-00980-2

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