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Inactivation of Sirt6 ameliorates muscular dystrophy in mdx mice by releasing suppression of utrophin expression

The NAD(+)-dependent SIRT1-7 family of protein deacetylases plays a vital role in various molecular pathways related to stress response, DNA repair, aging and metabolism. Increased activity of individual sirtuins often exerts beneficial effects in pathophysiological conditions whereas reduced activi...

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Detalles Bibliográficos
Autores principales:	Georgieva, Angelina M., Guo, Xinyue, Bartkuhn, Marek, Günther, Stefan, Künne, Carsten, Smolka, Christian, Atzberger, Ann, Gärtner, Ulrich, Mamchaoui, Kamel, Bober, Eva, Zhou, Yonggang, Yuan, Xuejun, Braun, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300598/ https://www.ncbi.nlm.nih.gov/pubmed/35859073 http://dx.doi.org/10.1038/s41467-022-31798-z

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