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Simulating the chromatin-mediated phase separation of model proteins with multiple domains
We perform simulations of a system containing simple model proteins and a polymer representing chromatin. We study the interplay between protein-protein and protein-chromatin interactions, and the resulting condensates that arise due to liquid-liquid phase separation, or a via a “bridging-induced at...
Autores principales: | Ancona, Marco, Brackley, Chris A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300671/ https://www.ncbi.nlm.nih.gov/pubmed/35643628 http://dx.doi.org/10.1016/j.bpj.2022.05.039 |
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