Thiostrepton induces ferroptosis in pancreatic cancer cells through STAT3/GPX4 signalling

Ferroptosis is a new form of regulated cell death that is mediated by intracellular iron and ester oxygenase, and glutathione-dependent lipid hydroperoxidase glutathione peroxidase 4 (GPX4) prevents ferroptosis by converting lipid hydroperoxides into nontoxic lipid alcohols. Although thiostrepton (T...

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Detalles Bibliográficos
Autores principales: Zhang, Weifan, Gong, Mengyuan, Zhang, Wunai, Mo, Jiantao, Zhang, Simei, Zhu, Zeen, Wang, Xueni, Zhang, Bo, Qian, Weikun, Wu, Zheng, Ma, Qingyong, Wang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300693/
https://www.ncbi.nlm.nih.gov/pubmed/35859150
http://dx.doi.org/10.1038/s41419-022-05082-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300693/
https://www.ncbi.nlm.nih.gov/pubmed/35859150
http://dx.doi.org/10.1038/s41419-022-05082-3

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