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Multi-task deep learning for glaucoma detection from color fundus images

Glaucoma is an eye condition that leads to loss of vision and blindness if not diagnosed in time. Diagnosis requires human experts to estimate in a limited time subtle changes in the shape of the optic disc from retinal fundus images. Deep learning methods have been satisfactory in classifying and s...

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Autores principales: Pascal, Lucas, Perdomo, Oscar J., Bost, Xavier, Huet, Benoit, Otálora, Sebastian, Zuluaga, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300731/
https://www.ncbi.nlm.nih.gov/pubmed/35858986
http://dx.doi.org/10.1038/s41598-022-16262-8
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author Pascal, Lucas
Perdomo, Oscar J.
Bost, Xavier
Huet, Benoit
Otálora, Sebastian
Zuluaga, Maria A.
author_facet Pascal, Lucas
Perdomo, Oscar J.
Bost, Xavier
Huet, Benoit
Otálora, Sebastian
Zuluaga, Maria A.
author_sort Pascal, Lucas
collection PubMed
description Glaucoma is an eye condition that leads to loss of vision and blindness if not diagnosed in time. Diagnosis requires human experts to estimate in a limited time subtle changes in the shape of the optic disc from retinal fundus images. Deep learning methods have been satisfactory in classifying and segmenting diseases in retinal fundus images, assisting in analyzing the increasing amount of images. Model training requires extensive annotations to achieve successful generalization, which can be highly problematic given the costly expert annotations. This work aims at designing and training a novel multi-task deep learning model that leverages the similarities of related eye-fundus tasks and measurements used in glaucoma diagnosis. The model simultaneously learns different segmentation and classification tasks, thus benefiting from their similarity. The evaluation of the method in a retinal fundus glaucoma challenge dataset, including 1200 retinal fundus images from different cameras and medical centers, obtained a [Formula: see text] AUC performance compared to an [Formula: see text] obtained by the same backbone network trained to detect glaucoma. Our approach outperforms other multi-task learning models, and its performance pairs with trained experts using [Formula: see text] times fewer parameters than training each task separately. The data and the code for reproducing our results are publicly available.
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spelling pubmed-93007312022-07-22 Multi-task deep learning for glaucoma detection from color fundus images Pascal, Lucas Perdomo, Oscar J. Bost, Xavier Huet, Benoit Otálora, Sebastian Zuluaga, Maria A. Sci Rep Article Glaucoma is an eye condition that leads to loss of vision and blindness if not diagnosed in time. Diagnosis requires human experts to estimate in a limited time subtle changes in the shape of the optic disc from retinal fundus images. Deep learning methods have been satisfactory in classifying and segmenting diseases in retinal fundus images, assisting in analyzing the increasing amount of images. Model training requires extensive annotations to achieve successful generalization, which can be highly problematic given the costly expert annotations. This work aims at designing and training a novel multi-task deep learning model that leverages the similarities of related eye-fundus tasks and measurements used in glaucoma diagnosis. The model simultaneously learns different segmentation and classification tasks, thus benefiting from their similarity. The evaluation of the method in a retinal fundus glaucoma challenge dataset, including 1200 retinal fundus images from different cameras and medical centers, obtained a [Formula: see text] AUC performance compared to an [Formula: see text] obtained by the same backbone network trained to detect glaucoma. Our approach outperforms other multi-task learning models, and its performance pairs with trained experts using [Formula: see text] times fewer parameters than training each task separately. The data and the code for reproducing our results are publicly available. Nature Publishing Group UK 2022-07-20 /pmc/articles/PMC9300731/ /pubmed/35858986 http://dx.doi.org/10.1038/s41598-022-16262-8 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Pascal, Lucas
Perdomo, Oscar J.
Bost, Xavier
Huet, Benoit
Otálora, Sebastian
Zuluaga, Maria A.
Multi-task deep learning for glaucoma detection from color fundus images
title Multi-task deep learning for glaucoma detection from color fundus images
title_full Multi-task deep learning for glaucoma detection from color fundus images
title_fullStr Multi-task deep learning for glaucoma detection from color fundus images
title_full_unstemmed Multi-task deep learning for glaucoma detection from color fundus images
title_short Multi-task deep learning for glaucoma detection from color fundus images
title_sort multi-task deep learning for glaucoma detection from color fundus images
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300731/
https://www.ncbi.nlm.nih.gov/pubmed/35858986
http://dx.doi.org/10.1038/s41598-022-16262-8
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