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An epigenome-wide view of osteoarthritis in primary tissues

Osteoarthritis is a complex degenerative joint disease. Here, we investigate matched genotype and methylation profiles of primary chondrocytes from macroscopically intact (low-grade) and degraded (high-grade) osteoarthritis cartilage and from synoviocytes collected from 98 osteoarthritis-affected in...

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Detalles Bibliográficos
Autores principales:	Kreitmaier, Peter, Suderman, Matthew, Southam, Lorraine, Coutinho de Almeida, Rodrigo, Hatzikotoulas, Konstantinos, Meulenbelt, Ingrid, Steinberg, Julia, Relton, Caroline L., Wilkinson, J. Mark, Zeggini, Eleftheria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300761/ https://www.ncbi.nlm.nih.gov/pubmed/35679866 http://dx.doi.org/10.1016/j.ajhg.2022.05.010

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