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Luteolin Binds Streptolysin O Toxin and Inhibits Its Hemolytic Effects and Cytotoxicity

Group A streptococcus (GAS, Streptococcus pyogenes) is a common pathogen that can cause a variety of human diseases. Streptolysin O (SLO) is an exotoxin produced by GAS. It is a pore-forming toxin (PFT) that exhibits high in vivo toxicity. SLO enables GAS to evade phagocytosis and clearance by neutr...

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Detalles Bibliográficos
Autores principales: Guo, Tingting, Liu, Peng, Wang, Zeyu, Zheng, Yuling, Huang, Wenhua, Kong, Decong, Ding, Lizhong, Lv, Qingyu, Wang, Zhongtian, Jiang, Hua, Jiang, Yongqiang, Sun, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300923/
https://www.ncbi.nlm.nih.gov/pubmed/35873567
http://dx.doi.org/10.3389/fphar.2022.942180