FEV Maintains Homing and Expansion by Activating ITGA4 Transcription in Primary and Relapsed AML

Acute myeloid leukemia (AML) is an aggressive hematological malignancy that recurs in approximately 50% of cases. Elevated homing and uncontrolled expansion are characteristics of AML cells. Here, we identified that Fifth Ewing Variant (FEV) regulates the homing and expansion of AML cells. We found...

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Detalles Bibliográficos
Autores principales: Zhang, Jubin, Qi, Lijuan, Wang, Tanzhen, An, Jingnan, Zhou, Biqi, Fang, Yanglan, Liu, Yujie, Shan, Meng, Hong, Dengli, Wu, Depei, Xu, Yang, Liu, Tianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300928/
https://www.ncbi.nlm.nih.gov/pubmed/35875066
http://dx.doi.org/10.3389/fonc.2022.890346

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